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The finding of Beau’s lines may indicate previous severe illness, trauma, or disclosure to cold temperatures in patients with Raynaud’s disease. In the petit mal epilepsy of trauma or psoriasis, onycholysis should prompt a search for symptoms of hyperthyroidism. Koilonychia, or “spoon-shaped” nails, may stimulate a work-up for iron-storage disease or anemia.
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Nail Abnormalities: Clues to Systemic Disease - American Family Physician